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69 Best Startups in Groton Massachusetts to Watch in 2025

The Definitive ÐÓ°ÉÔ­´´ Ranking of Startups in Groton Massachusetts

We track 71,000+ companies and rank them dynamically using our ÐÓ°ÉÔ­´´ Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 140 start-ups with an aggregate funding of $5.7b. The average funding per company in this subset is $82.9m.

Last update to the database: Feb 18, 2025. See changelog.

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6

Funding Rounds

$44.8m

Money raised

VoltDB is a Bedford, Massachusetts-based developer of an in-memory SQL and relational database offering transaction processing in a horizontal scale-out platform.

Key people:

6

Funding Rounds

$678.5m

Money raised

Klaviyo is a marketing automation software company which has a email software platform with SMS for ecommerce companies.

Location:

Key people:

13

Funding Rounds

$386.6m

Money raised

A biotechnology company that develops medicines based on live bacterial consortia that can colonize the human intestine.

5

Funding Rounds

$111.8m

Money raised

Orig3n is a biotechnology company developing personalized regenerative medicine treatments based on patient genetic profiles.

5

Funding Rounds

$68.7m

Money raised

AOBiome Therapeutics is a therapeutics company, based in Newton, Massachusetts and founded in 2013, that developed strains of Ammonia Oxidizing Bacteria (AOB) to administer live in treatments that address inflammatory conditions.

Key people:

5

Funding Rounds

$217.0m

Money raised

Takeoff Technologies provides an automated grocery fulfillment solution for grocers.

3

Funding Rounds

$109.0m

Money raised

Dyno Therapeutics is a company based in Cambridge, Massachusetts applying artificial intelligence to gene therapy, focused on adeno-associated virus capsid engineering.

2

Funding Rounds

$2.0m

Money raised

Antera Therapeutics is an allergy prevention development company.

2

Funding Rounds

$24.5m

Money raised

An insurance technology company offering a platform for employee benefits and insurance.

Key people:

3

Funding Rounds

$127.6m

Money raised

An insurance technology company offering a platform for comparing and purchasing automobile insurance.

5

Funding Rounds

$32.5m

Money raised

Fortify is a Boston-based 3D printing company that has the goal to enable fabrication of composites with optimized microstructures

4

Funding Rounds

$64.5m

Money raised

Alfresco is a software company founded in 2005 by John Newton, John Newton and John Powell.

2

Funding Rounds

$72.0m

Money raised

AlgoSec is a Ridgefield Park, New Jersey-based developer of network security software automating security policy management and business applications and ensuring security compliance.

2

Funding Rounds

$290.0k

Money raised

Beagle Learning is a Boston, Massachusetts-based company that provides a learning and collaboration platform for higher education institutions, corporations, and the military.

Location:

Key people:

8

Funding Rounds

$33.8m

Money raised

Apptopia is a company founded in 2011 by Eliran Sapir.

3

Funding Rounds

$6.0m

Money raised

A company utilizing BMI and Neurofeedback to optimize brain potential.

3

Funding Rounds

$105.0m

Money raised

A biopharmaceutical company developing therapeutics for treating age-related diseases.

3

Funding Rounds

$90.2m

Money raised

Chiasma Pharma is a Waltham, Massachusetts-based biopharmaceutical company developing oral drugs for the treatment of orphan diseases.

2

Funding Rounds

$91.5m

Money raised

Design, integrate, and automate document workflows using a single platform.

2

Funding Rounds

$67.5m

Money raised

An insurance technology company offering a platform for comparing and purchasing automobile and property insurance.

11

Funding Rounds

$35.7m

Money raised

Lightpoint Medical is a solutions developer and provider for the health care industry, specializing in the development of intra-operative, robot-guided systems.

Key people:

10

Funding Rounds

$786.3m

Money raised

A quantum physics and AI drug research and development company

5

Funding Rounds

$162.0m

Money raised

Sense is a Cambridge, Massachusetts-based developer and distributor of energy tracking and automation solutions. Sense specializes in tracking devices and home automation solutions for its customers.

4

Funding Rounds

$226.0m

Money raised

Arrakis is developing RNA-targeted small molecule (rSM) therapies to millions of patients.

2

Funding Rounds

$155.5m

Money raised

Frontier Medicines is a biopharmaceutical company developing chemoproteomics for drug discovery founded in 2018.

7

Funding Rounds

$24.6m

Money raised

Jazz is a company founded in 2009 by Don Charlton.

2

Funding Rounds

$71.0m

Money raised

nference is a Cambridge-based knowledge synthesis software platform that extracts insights from biomedical literature.

9

Funding Rounds

$90.0m

Money raised

Visible Measures is a Massachusetts-based company founded in 2005 by Brian Shin.

Industries:

Location:

Key people:

1

Funding Rounds

$3.0m

Money raised

Business to business managed marketplace company focused on Africa. WaystoCap was founded in 2014, it is headquartered in Casablanca, Morocco.

Industries:

Key people:

5

Funding Rounds

$80.2m

Money raised

Humantics is a software company that was founded in 2015.

5

Funding Rounds

$9.7m

Money raised

CrowdComfort is a company founded in 2013 by B. Eric Graham.

Location:

Key people:

1

Funding Rounds

An education platform for senior care training CareAcademy offers an online training empowering senior care professionals to deliver the highest caliber of services.

3

Funding Rounds

$27.5m

Money raised

Indico is a venture-backed startup that aims to apply machine learning into practical use within the enterprise.

2

Funding Rounds

$2.4m

Money raised

A biotechnology company developing technology platforms to improve therapeutics discovery and manufacturing.

4

Funding Rounds

$18.9m

Money raised

A company offering a voice first care management platform that is headquartered in Boston, Massachusetts and was founded in 2014 by Dr. Aiden Feng, Emanuele Musini, and James Wyman.

7

Funding Rounds

$27.5m

Money raised

Raptor Maps is a company that is building software with the use of drones and machine vision to help farms increase productivity.

2

Funding Rounds

$125.8m

Money raised

Mavrck is an all-in-one influencer marketing platform enabling marketers to identify & collaborate with influencers, advocates, referrers, and loyalists.

Key people:

2

Funding Rounds

$23.4m

Money raised

Voluntis is a company that is at the forefront of the medical and digital revolutions, the company is a pioneer in digital therapeutics.

Key people:

2

Funding Rounds

$3.5m

Money raised

A software company making human resource management software for small and medium sized businesses.

5

Funding Rounds

$108.3m

Money raised

RightHand Robotics is a company that provides the RightPick platform which combines advanced AI software with intelligent grippers and machine vision to ensure reliable throughput with seamless integrations.

5

Funding Rounds

$35.1m

Money raised

GRO Biosciences was founded by Dr. George Church at the Harvard Life Lab.

Key people:

3

Funding Rounds

$45.5m

Money raised

A company offering a medication management platform that gives insight into patient behavior.

2

Funding Rounds

$13.6m

Money raised

MSi is a specialized provider of next generation cyber defense solutions protecting control systems and critical physical assets in energy, transportation and defense.

9

Funding Rounds

$107.6m

Money raised

BG Medicine is a company developing diagnostic products for heart failure and related disorders.

Key people:

3

Funding Rounds

$28.0m

Money raised

Tamr is an enterprise software company that uses AI to enable enterprise companies with data scattered across multiple different databases to clean and integrate corporate data efficiently and accurately, making data that was formerly inaccessible available for corporate analytics and decision-making.

5

Funding Rounds

$291.7m

Money raised

Battery Resourcers is a company that offers a closed-loop cathode material supply chain solution

9

Funding Rounds

$41.3m

Money raised

MTPV develops and deploys thermophotovoltaic chips for the conversion of industrial waste heat into electricity.

9

Funding Rounds

$42.4m

Money raised

Kytopen is a mircrofluidics company founded in 2017 by Paulo Garcia.

4

Funding Rounds

$16.8m

Money raised

Skyhook is a company in Boston, Massachusetts, United States.

2

Funding Rounds

$17.7m

Money raised

iSee, a Massachusetts-based company, is an artificial intelligence technology company.

2

Funding Rounds

$55.0m

Money raised

Onapsis is a Boston-based cybersecurity and compliance solutions company.

4

Funding Rounds

$4.7m

Money raised

Aldatu Biosciences is a Cambridge, Massachusetts-based medical diagnostics company offering diagnostic tools and a proprietary genotyping platform.

1

Funding Rounds

$2.5m

Money raised

Spiro is a proactive relationship management platform that creates contacts, organizes, and prioritizes opportunities.

2

Funding Rounds

$222.0m

Money raised

Electric Hydrogen is a fossil-free hydrogen for a decarbonized world founded in 2020 by David Eaglesham, Derek Warnick, Dorian West and Raffi Garabedian.

6

Funding Rounds

$158.5m

Money raised

Company

3

Funding Rounds

$50.0m

Money raised

Neural Magic is a company founded in 2018 by Alexander Matveev.

4

Funding Rounds

$19.0m

Money raised

VIA is leveraging AI and blockchain to help utilities gain access to more comprehensive data insights and the intelligence needed to process it.

1

Funding Rounds

$17.0m

Money raised

QuEra is a fault-tolerant quantum computers developer founded in 2018 by John Pena.

2

Funding Rounds

$18.0m

Money raised

Edgewise Networks is a company that provides security against network threats.

2

Funding Rounds

$80.0m

Money raised

Uptycs is a Waltham, Massachusetts-based computer security company.

3

Funding Rounds

$28.0m

Money raised

Veo Robotics is a Waltham, Massachusetts-based company.

3

Funding Rounds

$26.0m

Money raised

XRHealth is a telemedicine startup that uses a VR platform that enables remote treatment. The XRHealth VR/AR telehealth platform is ISO certified, FDA certified and HIPAA compliant.

3

Funding Rounds

$1.4m

Money raised

Tamarin Health is a developer of digital health tools for Caregivers to create remote patient support networks.

1

Funding Rounds

$500.0k

Money raised

Global Enterprise software company delivering innovative Business Operations Management solutions

1

Funding Rounds

$10.0k

Money raised

VinylMint is a company that has developed a global marketplace

2

Funding Rounds

$51.7m

Money raised

Computational chemistry platform to develop small molecule therapeutics

1

Funding Rounds

$6.5m

Money raised

Abine is a company founded in 2010 by Rob Shavell, Eugene Kuznetsov and Andrew Sudbury.

3

Funding Rounds

$14.9m

Money raised

Nano-C is a company founded in 2001.

2

Funding Rounds

$7.2m

Money raised

Paerpay helps merchants accept contactless payments without the hassle of changing point-of-sales systems.

Industries:

Key people:

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